These adapters are made of Natural Kynar material. -Chemically resistant -Autoclavable -Meets USP Class VI requirements Natural Kynar material has a temperature range of -62°C to 107°C (-80 to 226°F), and a pressure of 260 psi at 21°C (70°F). This material can be autoclaved to 140°C (285°F) and meets USP Class VI requirements. Generally, chemically resistant to most acids, salts, weak bases, halogenated solvents, alcohols, nuclear and UV radiation, oxidants, ozone and deionized water. RoHS Compliant. USP Class VI.