These labels offer a highly reliable and irreversible indication of exposure to low temperatures. Labels clearly indicate when the product to which it is attached to has been subjected to harsh temperatures, which could have detrimental effects on refrigerated pharmaceuticals, foods, chemicals, paints, and adhesives. Available in both ascending and descending style accuracy is ±1 degree C of the rated temperature. Shelf life: one year after date of purchase. Warning: this product is not approved or intended for, and should not be used for medical, clinical, surgical or other patient oriented applications. Reliable proof that the product was maintained at the correct temperature used as a quick inspection tool that the product is in usable condition during the shipping and receiving process save time and money due to costly recalls self-adhesive design.